Lungs with inflamed vasculature
Lead focus · Clinical

Pathogen-induced pneumonia and ARDS

AV-001 is being developed for conditions where severe infection can trigger vascular leak, lung edema, inflammation and respiratory compromise.

Burn injury with vascular leakage at the cellular level
Expanded development

Severe burns and vascular leak-related injury

Development has expanded into severe burn resuscitation, where vascular leakage and fluid management are central clinical challenges.

Scientific relevance

The same biology may matter across

  • Acute lung injury
  • Host response to infection
  • Burn resuscitation
  • Wound & burn healing
  • Acute kidney injury
  • Hemorrhagic shock
  • Biotoxin exposure

AV-001 is investigational. Areas of scientific relevance reflect preclinical research and are not indications under clinical development unless stated.